引起狗狗肾结石的原因非常复杂，主要与宠物的饮食、运动量、遗传有关，另外宠物的饮食过于单一总是吃肉，不吃其他食物，饮食结构不合理，喝得太少，缺乏运动，或宠物本身有代谢遗传缺陷，肝功能下降；刺激慢性炎症。
此外，纯种宠物比血统不纯的宠物更容易患肾结石。
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